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Phosphoinositide 3-kinase in Health and Disease
Cancer, research
Signal Transduction
Cellular signal transduction
Enzymes
Effets physiologiques
Oncology
Biochemistry
Physiological effect
Therapeutic use
Medicine
Physiology
MEDICAL
From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in pro…
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